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Foundations in Precision Medicine Courses

3 Credits

Foundations of Precision Medicine: Genomic Technologies

Genomic technologies are emerging technologies used to manipulate and analyze genomic information. The course content will focus on current developments and emerging trends in genomic testing, clinical and research applications of emerging genomic tests, role of computing and data science, and applications of bioinformatics in genomics. The objective of this course is to help you understand how data from current and emerging genomic tests are generated, analyzed, stored, and potentially used to inform research or clinical decision-making strategies.

1 Credit

Medical Molecular Genetics

Provides foundational knowledge on human genetics/genomics, including pedigree analysis, non-Mendelian genetics, cytogenetics, polymorphism analysis, physical mapping and the human genome, mutation analysis and pathogenesis, genomic imprinting, viral and non-viral gene therapy.

1 Credit

Genetic Epidemiology

Reviews clinically important principles of genetic epidemiology, including population genetics, familial aggregation and heritability analysis, TagSNPs and haplotype blocks, population-based studies, GWAS and issues related to genetic association studies and epigenetics.

2 Credits

Precision Medicine Seminar

Consists of content presented at the UF Precision Medicine Conference. The seminar brings together precision medicine experts to provide the latest information and implications of discovery, trends, technologies, and clinical applications of genomic/genetic data. Although the graduate course and conference have separate components, students are welcome to attend the conference live. The graduate course included though provoking assignments and discussions, and a capstone project that furthers the discussions presented at the live conference.

Clinical Application Courses

3 credits

Clinical Applications of Precision Medicine: Precision Health

Reviews knowledge and applications of precision medicine diagnosis and treatment considerations of concepts in monogenic diseases and complex diseases. Important concepts include susceptibility genomics, diagnostic approaches, laboratory testing and treatment considerations for genomic medicine. Diseases include cystic fibrosis, monogenic diabetes, Marfan syndrome, Huntington’s disease, as well as cardiovascular, metabolic, neurologic, mental health disorders and addiction and others.

3 Credits

Clinical Applications of Precision Medicine: Oncology

Reviews knowledge and clinical applications of precision medicine approaches and technologies in diagnosing or treating cancer, including the genetics of cancer, targeted cancer treatments, somatic testing, current and future research and clinical trends and other information.

2 credits

Clinical Applications of Precision Medicine: Pharmacogenomics

Includes knowledge and clinical applications of pharmacogenomics in precision medicine, including its contribution to variability in drug metabolism, use of pharmacogenomics to identify patients at risk for adverse drug reactions and clinical use of pharmacogenomic data in drug therapy for multiple therapeutic areas, including cardiovascular.

Additional Course Electives

3 credits

Pharmacogenomics and Genomics Data Analysis

Utilizes the framework of pharmacogenomics to lay the foundation for understanding other types of omic and pharmaco-omic study designs and analyses. The course will use a combination of lectures, discussions of assigned literature, small group discussions, projects and student-led presentations. This courses is offered in person at UF College of Pharmacy Gainesville campus only.

2 credits

Case Studies in Clinical Pharmacogenomics

This course will provide an overview of the use of pharmacogenomic data to inform clinical and therapeutic decision making for gene-drug pairs across a range of conditions.

2 credits

Clinical Pharmacogenomics Implementation

Explore ways to implement use of pharmacogenetic tests in patient care. The course will address barriers to clinical implementation of pharmacogenetic tests by referencing appropriate guidelines and evidence-based and peer-review recourses.

3 Credits

Ethics in Drug Production, Distribution, and Use

This is an introduction to biomedical ethics primarily as applied to pharmaceutical and medical device products. Subject areas include the provider-patient relationship, clinical research ethics, distribution of scarce resources, ethics and industry, and beginning and end of life issues. Topics of special interest are tissue engineering and stem cells, human cloning, xenotransplantation, defining diseases, genetic testing, and genomically customized medications.

3 Credits

Pharmaceutical Research and Development: Foundations and Impact on Precision Medicine

This course provides a through introduction to the way modern pharmaceuticals (drugs) are discovered, developed, regulated, and marketed. It is intended to give the student an overview of how the pharmaceutical industry operates and the various functional roles of the people involved.

3 Credits

Literature Survey in Precision Medicine

This 3-credit course will provide an opportunity for students to demonstrate synthesis of foundational and concentration competencies through researching and writing a thesis paper that addresses a research or practice need in precision medicine.

1 Credit

Patient Education and Communication in the Era of Precision Medicine

Requirements and strategies for patient education in precision medicine are rapidly changing due to emerging technologies, new types of testing, and increasing availability to generalist providers. Content will focus on emerging issues in patient education and communication in precision medicine. Topics include review of traditional and emerging models of patient education in genetic testing, workforce educational needs and strategies, implications and communication strategies for areas of uncertainty (e.g., variants of unknown significance, test reimbursement), essential topics and strategies to consider for patient diversity and health disparities, and legal and ethical issues in patient education and communication in precision medicine.

3 Credits

Ethics in Genetics

The late 20th century rapid development of new genetic technologies that enabled the mapping and sequencing in the Human Genome Project, as well as non-human life forms has had a profound impact on human society and our self-understanding. This technology has sometimes proceeded at a pace that threatens to outstrip our collective wisdom as to how it should be assimilated and regulated, both for individuals and for organizational entities from reproductive clinics and labs to national research institutions and entire societies. This course will introduce participants to these issues and explore proposed solutions as well as, as yet unsolved, problems. The course will focus primarily on human medical applications, but will also include some topics in social contexts wider than an exclusively medical context. 

Special Topics (Master’s Degree)

1 credit

Special Topics in Personalized Medicine (exam ProctorU)

This required course must be taken in in the final semester, and students take a final comprehensive exam using ProctorU. Students should plan to take one elective in addition to this required course to meet the University of Florida graduation requirements.

Course Offerings

Course #Course TitleCreditsSpringSummerFall
PHA 6136Clinical Applications of Precision Medicine: Oncology3x
PHA 6613Clinical Applications of Precision Medicine: Precision Health3x
PHA 6935Ethics in Drug Production, Distribution, and Use3xx
PHA 6935Ethics in Genetics3x
PHA 6935Principles of Pharmacogenomics 3xxx
PHA 6935Applied Statistics for Data Analysis3xxx
PHA 6936Literature Survey in Precision Medicine3xxx
PHA 6936 Pharmaceutical Research and Development: Foundations and Impact on Precision Medicine 3xxx
PHA 6135Clinical Applications of Precision Medicine: Pharmacogenomic2x
PHA 6935Case Studies in Clinical Pharmacogenomics2xx
PHA 6935Clinical Pharmacogenomics Implementation2xx
PHA 6935Precision Medicine Seminar 2xx
PHA 6134Foundations of Precision Medicine: Genomic Technologies 1xxx
GMS 6224Foundations of Precision Medicine: Medical Molecular Genetics1xxx
PHA 6598Foundations of Precision Medicine: Genetic Epidemiology1xxx
PHA 6746 Patient Education and Communication in the Era of Precision Medicine1xx
PHA 6936Special Topics in Precision Medicine (exam ProctorU)1xxx
Last Updated: Fall 2021